
Genetics: From Genes to Genomes
by Hartwell, LelandRent Textbook
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Summary
Table of Contents
1 Genetics: The Study of Biological InformationPart 1 Basic Principles: How Traits Are Transmitted2 Mendel's Breakthrough: Patterns, Particles, and Principles of Heredity3 Extensions to Mendel: Complexities in Relating Genotype to Phenotype4 The Chromosome Theory of Inheritance5 Linkage, Recombination, and the Mapping of Genes on ChromosomesPart 2 What Genes Are and What They Do6 DNA: How the Molecule of Heredity Carries, Replicates, and Recombines Information 7 Anatomy and Function of a Gene: Dissection Through Mutation8 Gene Expression: The Flow of Genetic Information from DNA via RNA to ProteinPart 3 Genomes9 Deconstructing the Genome: DNA at High Resolution10 Reconstructing the Genome Through Genetic and Molecular Analysis11 The Direct Detection of Genotype Distinguishes Individual GenomesPart 4 How Genes Travel12 The Eukaryotic Chromosome: An Organelle for Packaging and Managing DNA13 Chromosomal Rearrangements and Changes in Chromosome Number Reshape Eukaryotic Genomes14 The Prokaryotic Chromosome: Genetic Analysis in Bacteria15 The Chromosomes of Organelles Outside the Nucleus Exhibit Non-Mendelian Patterns of InheritancePart 5 How Genes Are Regulated16 Gene Regulation in Prokaryotes17 Gene Regulation in Eukaryotes18 Cell-Cycle Regulation and the Genetics of Cancer19 Using Genetics to Study Development Part 6 How Genes Change20 The Genetic Analysis of Populations and How They Evolve21 Evolution at the Molecular LevelReference: Portraits of Model Eukaryotic OrganismsA Saccharomyces cerevisiae: Genetic Portrait of Yeast B Arabidopsis thaliana: Genetic Portrait of a Model Plant C Caenorhabditis elegans: Genetic Portrait of a Simple Multicellular Organism D Drosophila melanogaster: Genetic Portrait of the Fruit Fly E Mus musculus: Genetic Portrait of the House MouseGuidelines for Gene NomenclatureBrief Answer Section
2 Mendel's Breakthrough: Patterns, Particles, and Principles of Heredity3 Extensions to Mendel: Complexities in Relating Genotype to Phenotype4 The Chromosome Theory of Inheritance5 Linkage, Recombination, and the Mapping of Genes on ChromosomesPart 2 What Genes Are and What They Do6 DNA: How the Molecule of Heredity Carries, Replicates, and Recombines Information 7 Anatomy and Function of a Gene: Dissection Through Mutation8 Gene Expression: The Flow of Genetic Information from DNA via RNA to ProteinPart 3 Genomes9 Deconstructing the Genome: DNA at High Resolution10 Reconstructing the Genome Through Genetic and Molecular Analysis11 The Direct Detection of Genotype Distinguishes Individual GenomesPart 4 How Genes Travel12 The Eukaryotic Chromosome: An Organelle for Packaging and Managing DNA13 Chromosomal Rearrangements and Changes in Chromosome Number Reshape Eukaryotic Genomes14 The Prokaryotic Chromosome: Genetic Analysis in Bacteria15 The Chromosomes of Organelles Outside the Nucleus Exhibit Non-Mendelian Patterns of InheritancePart 5 How Genes Are Regulated16 Gene Regulation in Prokaryotes17 Gene Regulation in Eukaryotes18 Cell-Cycle Regulation and the Genetics of Cancer19 Using Genetics to Study Development Part 6 How Genes Change20 The Genetic Analysis of Populations and How They Evolve21 Evolution at the Molecular LevelReference: Portraits of Model Eukaryotic OrganismsA Saccharomyces cerevisiae: Genetic Portrait of Yeast B Arabidopsis thaliana: Genetic Portrait of a Model Plant C Caenorhabditis elegans: Genetic Portrait of a Simple Multicellular Organism D Drosophila melanogaster: Genetic Portrait of the Fruit Fly E Mus musculus: Genetic Portrait of the House MouseGuidelines for Gene NomenclatureBrief Answer Section
4 The Chromosome Theory of Inheritance5 Linkage, Recombination, and the Mapping of Genes on ChromosomesPart 2 What Genes Are and What They Do6 DNA: How the Molecule of Heredity Carries, Replicates, and Recombines Information 7 Anatomy and Function of a Gene: Dissection Through Mutation8 Gene Expression: The Flow of Genetic Information from DNA via RNA to ProteinPart 3 Genomes9 Deconstructing the Genome: DNA at High Resolution10 Reconstructing the Genome Through Genetic and Molecular Analysis11 The Direct Detection of Genotype Distinguishes Individual GenomesPart 4 How Genes Travel12 The Eukaryotic Chromosome: An Organelle for Packaging and Managing DNA13 Chromosomal Rearrangements and Changes in Chromosome Number Reshape Eukaryotic Genomes14 The Prokaryotic Chromosome: Genetic Analysis in Bacteria15 The Chromosomes of Organelles Outside the Nucleus Exhibit Non-Mendelian Patterns of InheritancePart 5 How Genes Are Regulated16 Gene Regulation in Prokaryotes17 Gene Regulation in Eukaryotes18 Cell-Cycle Regulation and the Genetics of Cancer19 Using Genetics to Study Development Part 6 How Genes Change20 The Genetic Analysis of Populations and How They Evolve21 Evolution at the Molecular LevelReference: Portraits of Model Eukaryotic OrganismsA Saccharomyces cerevisiae: Genetic Portrait of Yeast B Arabidopsis thaliana: Genetic Portrait of a Model Plant C Caenorhabditis elegans: Genetic Portrait of a Simple Multicellular Organism D Drosophila melanogaster: Genetic Portrait of the Fruit Fly E Mus musculus: Genetic Portrait of the House MouseGuidelines for Gene NomenclatureBrief Answer Section
Part 2 What Genes Are and What They Do6 DNA: How the Molecule of Heredity Carries, Replicates, and Recombines Information 7 Anatomy and Function of a Gene: Dissection Through Mutation8 Gene Expression: The Flow of Genetic Information from DNA via RNA to ProteinPart 3 Genomes9 Deconstructing the Genome: DNA at High Resolution10 Reconstructing the Genome Through Genetic and Molecular Analysis11 The Direct Detection of Genotype Distinguishes Individual GenomesPart 4 How Genes Travel12 The Eukaryotic Chromosome: An Organelle for Packaging and Managing DNA13 Chromosomal Rearrangements and Changes in Chromosome Number Reshape Eukaryotic Genomes14 The Prokaryotic Chromosome: Genetic Analysis in Bacteria15 The Chromosomes of Organelles Outside the Nucleus Exhibit Non-Mendelian Patterns of InheritancePart 5 How Genes Are Regulated16 Gene Regulation in Prokaryotes17 Gene Regulation in Eukaryotes18 Cell-Cycle Regulation and the Genetics of Cancer19 Using Genetics to Study Development Part 6 How Genes Change20 The Genetic Analysis of Populations and How They Evolve21 Evolution at the Molecular LevelReference: Portraits of Model Eukaryotic OrganismsA Saccharomyces cerevisiae: Genetic Portrait of Yeast B Arabidopsis thaliana: Genetic Portrait of a Model Plant C Caenorhabditis elegans: Genetic Portrait of a Simple Multicellular Organism D Drosophila melanogaster: Genetic Portrait of the Fruit Fly E Mus musculus: Genetic Portrait of the House MouseGuidelines for Gene NomenclatureBrief Answer Section
7 Anatomy and Function of a Gene: Dissection Through Mutation8 Gene Expression: The Flow of Genetic Information from DNA via RNA to ProteinPart 3 Genomes9 Deconstructing the Genome: DNA at High Resolution10 Reconstructing the Genome Through Genetic and Molecular Analysis11 The Direct Detection of Genotype Distinguishes Individual GenomesPart 4 How Genes Travel12 The Eukaryotic Chromosome: An Organelle for Packaging and Managing DNA13 Chromosomal Rearrangements and Changes in Chromosome Number Reshape Eukaryotic Genomes14 The Prokaryotic Chromosome: Genetic Analysis in Bacteria15 The Chromosomes of Organelles Outside the Nucleus Exhibit Non-Mendelian Patterns of InheritancePart 5 How Genes Are Regulated16 Gene Regulation in Prokaryotes17 Gene Regulation in Eukaryotes18 Cell-Cycle Regulation and the Genetics of Cancer19 Using Genetics to Study Development Part 6 How Genes Change20 The Genetic Analysis of Populations and How They Evolve21 Evolution at the Molecular LevelReference: Portraits of Model Eukaryotic OrganismsA Saccharomyces cerevisiae: Genetic Portrait of Yeast B Arabidopsis thaliana: Genetic Portrait of a Model Plant C Caenorhabditis elegans: Genetic Portrait of a Simple Multicellular Organism D Drosophila melanogaster: Genetic Portrait of the Fruit Fly E Mus musculus: Genetic Portrait of the House MouseGuidelines for Gene NomenclatureBrief Answer Section
Part 3 Genomes9 Deconstructing the Genome: DNA at High Resolution10 Reconstructing the Genome Through Genetic and Molecular Analysis11 The Direct Detection of Genotype Distinguishes Individual GenomesPart 4 How Genes Travel12 The Eukaryotic Chromosome: An Organelle for Packaging and Managing DNA13 Chromosomal Rearrangements and Changes in Chromosome Number Reshape Eukaryotic Genomes14 The Prokaryotic Chromosome: Genetic Analysis in Bacteria15 The Chromosomes of Organelles Outside the Nucleus Exhibit Non-Mendelian Patterns of InheritancePart 5 How Genes Are Regulated16 Gene Regulation in Prokaryotes17 Gene Regulation in Eukaryotes18 Cell-Cycle Regulation and the Genetics of Cancer19 Using Genetics to Study Development Part 6 How Genes Change20 The Genetic Analysis of Populations and How They Evolve21 Evolution at the Molecular LevelReference: Portraits of Model Eukaryotic OrganismsA Saccharomyces cerevisiae: Genetic Portrait of Yeast B Arabidopsis thaliana: Genetic Portrait of a Model Plant C Caenorhabditis elegans: Genetic Portrait of a Simple Multicellular Organism D Drosophila melanogaster: Genetic Portrait of the Fruit Fly E Mus musculus: Genetic Portrait of the House MouseGuidelines for Gene NomenclatureBrief Answer Section
10 Reconstructing the Genome Through Genetic and Molecular Analysis11 The Direct Detection of Genotype Distinguishes Individual GenomesPart 4 How Genes Travel12 The Eukaryotic Chromosome: An Organelle for Packaging and Managing DNA13 Chromosomal Rearrangements and Changes in Chromosome Number Reshape Eukaryotic Genomes14 The Prokaryotic Chromosome: Genetic Analysis in Bacteria15 The Chromosomes of Organelles Outside the Nucleus Exhibit Non-Mendelian Patterns of InheritancePart 5 How Genes Are Regulated16 Gene Regulation in Prokaryotes17 Gene Regulation in Eukaryotes18 Cell-Cycle Regulation and the Genetics of Cancer19 Using Genetics to Study Development Part 6 How Genes Change20 The Genetic Analysis of Populations and How They Evolve21 Evolution at the Molecular LevelReference: Portraits of Model Eukaryotic OrganismsA Saccharomyces cerevisiae: Genetic Portrait of Yeast B Arabidopsis thaliana: Genetic Portrait of a Model Plant C Caenorhabditis elegans: Genetic Portrait of a Simple Multicellular Organism D Drosophila melanogaster: Genetic Portrait of the Fruit Fly E Mus musculus: Genetic Portrait of the House MouseGuidelines for Gene NomenclatureBrief Answer Section
Part 4 How Genes Travel12 The Eukaryotic Chromosome: An Organelle for Packaging and Managing DNA13 Chromosomal Rearrangements and Changes in Chromosome Number Reshape Eukaryotic Genomes14 The Prokaryotic Chromosome: Genetic Analysis in Bacteria15 The Chromosomes of Organelles Outside the Nucleus Exhibit Non-Mendelian Patterns of InheritancePart 5 How Genes Are Regulated16 Gene Regulation in Prokaryotes17 Gene Regulation in Eukaryotes18 Cell-Cycle Regulation and the Genetics of Cancer19 Using Genetics to Study Development Part 6 How Genes Change20 The Genetic Analysis of Populations and How They Evolve21 Evolution at the Molecular LevelReference: Portraits of Model Eukaryotic OrganismsA Saccharomyces cerevisiae: Genetic Portrait of Yeast B Arabidopsis thaliana: Genetic Portrait of a Model Plant C Caenorhabditis elegans: Genetic Portrait of a Simple Multicellular Organism D Drosophila melanogaster: Genetic Portrait of the Fruit Fly E Mus musculus: Genetic Portrait of the House MouseGuidelines for Gene NomenclatureBrief Answer Section
13 Chromosomal Rearrangements and Changes in Chromosome Number Reshape Eukaryotic Genomes14 The Prokaryotic Chromosome: Genetic Analysis in Bacteria15 The Chromosomes of Organelles Outside the Nucleus Exhibit Non-Mendelian Patterns of InheritancePart 5 How Genes Are Regulated16 Gene Regulation in Prokaryotes17 Gene Regulation in Eukaryotes18 Cell-Cycle Regulation and the Genetics of Cancer19 Using Genetics to Study Development Part 6 How Genes Change20 The Genetic Analysis of Populations and How They Evolve21 Evolution at the Molecular LevelReference: Portraits of Model Eukaryotic OrganismsA Saccharomyces cerevisiae: Genetic Portrait of Yeast B Arabidopsis thaliana: Genetic Portrait of a Model Plant C Caenorhabditis elegans: Genetic Portrait of a Simple Multicellular Organism D Drosophila melanogaster: Genetic Portrait of the Fruit Fly E Mus musculus: Genetic Portrait of the House MouseGuidelines for Gene NomenclatureBrief Answer Section
15 The Chromosomes of Organelles Outside the Nucleus Exhibit Non-Mendelian Patterns of InheritancePart 5 How Genes Are Regulated16 Gene Regulation in Prokaryotes17 Gene Regulation in Eukaryotes18 Cell-Cycle Regulation and the Genetics of Cancer19 Using Genetics to Study Development Part 6 How Genes Change20 The Genetic Analysis of Populations and How They Evolve21 Evolution at the Molecular LevelReference: Portraits of Model Eukaryotic OrganismsA Saccharomyces cerevisiae: Genetic Portrait of Yeast B Arabidopsis thaliana: Genetic Portrait of a Model Plant C Caenorhabditis elegans: Genetic Portrait of a Simple Multicellular Organism D Drosophila melanogaster: Genetic Portrait of the Fruit Fly E Mus musculus: Genetic Portrait of the House MouseGuidelines for Gene NomenclatureBrief Answer Section
16 Gene Regulation in Prokaryotes17 Gene Regulation in Eukaryotes18 Cell-Cycle Regulation and the Genetics of Cancer19 Using Genetics to Study Development Part 6 How Genes Change20 The Genetic Analysis of Populations and How They Evolve21 Evolution at the Molecular LevelReference: Portraits of Model Eukaryotic OrganismsA Saccharomyces cerevisiae: Genetic Portrait of Yeast B Arabidopsis thaliana: Genetic Portrait of a Model Plant C Caenorhabditis elegans: Genetic Portrait of a Simple Multicellular Organism D Drosophila melanogaster: Genetic Portrait of the Fruit Fly E Mus musculus: Genetic Portrait of the House MouseGuidelines for Gene NomenclatureBrief Answer Section
18 Cell-Cycle Regulation and the Genetics of Cancer19 Using Genetics to Study Development Part 6 How Genes Change20 The Genetic Analysis of Populations and How They Evolve21 Evolution at the Molecular LevelReference: Portraits of Model Eukaryotic OrganismsA Saccharomyces cerevisiae: Genetic Portrait of Yeast B Arabidopsis thaliana: Genetic Portrait of a Model Plant C Caenorhabditis elegans: Genetic Portrait of a Simple Multicellular Organism D Drosophila melanogaster: Genetic Portrait of the Fruit Fly E Mus musculus: Genetic Portrait of the House MouseGuidelines for Gene NomenclatureBrief Answer Section
Part 6 How Genes Change20 The Genetic Analysis of Populations and How They Evolve21 Evolution at the Molecular LevelReference: Portraits of Model Eukaryotic OrganismsA Saccharomyces cerevisiae: Genetic Portrait of Yeast B Arabidopsis thaliana: Genetic Portrait of a Model Plant C Caenorhabditis elegans: Genetic Portrait of a Simple Multicellular Organism D Drosophila melanogaster: Genetic Portrait of the Fruit Fly E Mus musculus: Genetic Portrait of the House MouseGuidelines for Gene NomenclatureBrief Answer Section
21 Evolution at the Molecular LevelReference: Portraits of Model Eukaryotic OrganismsA Saccharomyces cerevisiae: Genetic Portrait of Yeast B Arabidopsis thaliana: Genetic Portrait of a Model Plant C Caenorhabditis elegans: Genetic Portrait of a Simple Multicellular Organism D Drosophila melanogaster: Genetic Portrait of the Fruit Fly E Mus musculus: Genetic Portrait of the House MouseGuidelines for Gene NomenclatureBrief Answer Section
A Saccharomyces cerevisiae: Genetic Portrait of Yeast B Arabidopsis thaliana: Genetic Portrait of a Model Plant C Caenorhabditis elegans: Genetic Portrait of a Simple Multicellular Organism D Drosophila melanogaster: Genetic Portrait of the Fruit Fly E Mus musculus: Genetic Portrait of the House MouseGuidelines for Gene NomenclatureBrief Answer Section
C Caenorhabditis elegans: Genetic Portrait of a Simple Multicellular Organism D Drosophila melanogaster: Genetic Portrait of the Fruit Fly E Mus musculus: Genetic Portrait of the House MouseGuidelines for Gene NomenclatureBrief Answer Section
E Mus musculus: Genetic Portrait of the House MouseGuidelines for Gene NomenclatureBrief Answer Section
Brief Answer Section
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