How can you lose weight, ease chronic conditions, and stay healthier longer? Discover how to “rewrite your health destiny” (David Perlmutter, MD, #1 New York Times bestselling author of Grain Brain) with this accessible book that teaches you how to flip the switch on your metabolism with intermittent fasting, protein cycling, and keto.

Within each of us is an ancient mechanism that eliminates toxic materials, initiates fat burning, and protects cells from becoming dysfunctional—or turning cancerous. It’s called autophagy, and when it’s turned on, the complex operation not only can slow down the aging process, it can optimize biological function as a whole, helping to stave off all manner of diseases and affording us the healthy life spans we never thought possible. It’s the body’s ultimate switch to life.

So how can we positively activate this switch? How frequently should we fast and for how long? Which foods dial up autophagy or, conversely, turn it down? How much exercise and what types are recommended? What’s the sweet spot between intermittent fasting, protein cycling, and ketogenic eating?

Backed by a wealth of scientific data and featuring a gallery of guidelines to follow for lasting results, “The Switch offers a paradigm shift in the way we think about health—and how to avoid decline and illness. This is a must read” (Mark Hyman, #1 New York Times bestselling author).

James W. Clement is a lawyer and entrepreneur turned research scientist who has devoted the past two decades to understanding the science of life extension. He is best known for his Supercentenarian Research Study, which he started in 2010 with Professor George M. Church of Harvard Medical School. Through worldwide collaborations and in his own laboratory in Gainesville, Florida, he focuses on advancing cutting-edge biomedical discoveries so that humanity can take advantage of these antiaging breakthroughs. Visit him at JamesWClement.com or follow him on Twitter @JamesWClement.

Kristin Loberg has collaborated on a lengthy list of New York Times bestselling books, including Dr. David Perlmutter’s Grain Brain and Dr. David B. Agus’s The End of Illness and A Short Guide to a Long Life.